October 1, 2025

Global Startup Ecosystem Report 2025

The GSER 2025, now in its 13th year, provides a comprehensive analysis of global startup ecosystems, drawing insights from 5 million startups across 350+ ecosystems and over a decade of research.

The report highlights the major trends, challenges, and opportunities shaping the global innovation landscape.

Global Trends

  • Ecosystem Value Decline: Global startup ecosystem value has dropped 31% since the last report due to fewer and smaller exits and post-COVID valuation corrections. However, since 2019, ecosystem value has still grown at a 11% annual rate, far outpacing the broader economy.

  • Regional Shifts: Asia and Africa are on the rise, while Europe and North America have seen declines.

    • Asia’s ecosystems, especially Beijing, Shenzhen, and Bengaluru, show strong gains.

    • Europe saw a 24% drop, though Paris climbed in global rankings.

    • Latin America’s ecosystem value fell the most, down 45%.

  • AI Dominance: AI is now the fastest-growing sector, attracting 40% of all VC funding (up from 26% in 2021). AI startups receive faster, larger rounds and are driving the next wave of ecosystem growth.

  • Other Sector Movements:


    • Life Sciences (+17%) and Cybersecurity (+4%) saw funding growth.

    • Cleantech (-40%) and Edtech (-57%) saw major declines.

    • Blockchain funding growth is flat year-over-year but still growing over a five-year horizon.

  • Funding Shifts:


    • Early-stage funding has contracted sharply since its 2021 peak.

    • Late-stage funding and exits are slowly recovering, though large exits (> $50M) remain down 31% globally compared to the last cycle.

Top Startup Ecosystems (2025 Ranking Highlights)

  1. Silicon Valley – Retains global dominance.

  2. New York City – Holds #2.

  3. London – Slips to #3 for the first time since 2019.

  4. Tel Aviv – Climbs to #4, continuing Israel’s upward trajectory.

  5. Boston (tied) and Beijing (tied) – Strong gains, driven by Life Sciences (Boston) and AI (Beijing).

Notable movers:

  • Hong Kong jumped from the Emerging list to #27 globally.

  • Philadelphia surged 12 spots to #13.

  • All major Chinese ecosystems (Beijing, Shanghai, Shenzhen, Hangzhou, Guangzhou) improved rankings.

Policy and Ecosystem Insights

  • Policy-driven ecosystems like Seoul, Singapore, Tokyo, Tel Aviv, and Melbourne are outpacing peers, proving the impact of strategic, AI-focused policies.

  • A global AI policy coalition has been launched to redirect AI budgets toward entrepreneurial startups (not just infrastructure and corporate R&D) to ensure local job creation and competitiveness.

Startup Genome emphasizes that ecosystems must rapidly transition to AI-native strategies to remain competitive. Bold policy moves, talent development, and founder-centric support will define the ecosystems that lead the next decade.

All updates