October 1, 2025
Global Startup Ecosystem Report 2025
The GSER 2025, now in its 13th year, provides a comprehensive analysis of global startup ecosystems, drawing insights from 5 million startups across 350+ ecosystems and over a decade of research.
The report highlights the major trends, challenges, and opportunities shaping the global innovation landscape.
Global Trends
- Ecosystem Value Decline: Global startup ecosystem value has dropped 31% since the last report due to fewer and smaller exits and post-COVID valuation corrections. However, since 2019, ecosystem value has still grown at a 11% annual rate, far outpacing the broader economy.
- Regional Shifts: Asia and Africa are on the rise, while Europe and North America have seen declines.
- Asia’s ecosystems, especially Beijing, Shenzhen, and Bengaluru, show strong gains.
- Europe saw a 24% drop, though Paris climbed in global rankings.
- Latin America’s ecosystem value fell the most, down 45%.
- Asia’s ecosystems, especially Beijing, Shenzhen, and Bengaluru, show strong gains.
- AI Dominance: AI is now the fastest-growing sector, attracting 40% of all VC funding (up from 26% in 2021). AI startups receive faster, larger rounds and are driving the next wave of ecosystem growth.
- Other Sector Movements:
- Life Sciences (+17%) and Cybersecurity (+4%) saw funding growth.
- Cleantech (-40%) and Edtech (-57%) saw major declines.
- Blockchain funding growth is flat year-over-year but still growing over a five-year horizon.
- Life Sciences (+17%) and Cybersecurity (+4%) saw funding growth.
- Funding Shifts:
- Early-stage funding has contracted sharply since its 2021 peak.
- Late-stage funding and exits are slowly recovering, though large exits (> $50M) remain down 31% globally compared to the last cycle.
- Early-stage funding has contracted sharply since its 2021 peak.
Top Startup Ecosystems (2025 Ranking Highlights)
- Silicon Valley – Retains global dominance.
- New York City – Holds #2.
- London – Slips to #3 for the first time since 2019.
- Tel Aviv – Climbs to #4, continuing Israel’s upward trajectory.
- Boston (tied) and Beijing (tied) – Strong gains, driven by Life Sciences (Boston) and AI (Beijing).
Notable movers:
- Hong Kong jumped from the Emerging list to #27 globally.
- Philadelphia surged 12 spots to #13.
- All major Chinese ecosystems (Beijing, Shanghai, Shenzhen, Hangzhou, Guangzhou) improved rankings.
Policy and Ecosystem Insights
- Policy-driven ecosystems like Seoul, Singapore, Tokyo, Tel Aviv, and Melbourne are outpacing peers, proving the impact of strategic, AI-focused policies.
- A global AI policy coalition has been launched to redirect AI budgets toward entrepreneurial startups (not just infrastructure and corporate R&D) to ensure local job creation and competitiveness.
Startup Genome emphasizes that ecosystems must rapidly transition to AI-native strategies to remain competitive. Bold policy moves, talent development, and founder-centric support will define the ecosystems that lead the next decade.
All updates